Tumor immune microenvironment and PD-1/PD-L1 treatment response
tumor cells, CD8+ T cells, TAM macrophages, the PD-1/PD-L1 immune checkpoint, anti-PD-1 therapy, cytotoxic killing, and tumor apoptosis as one coherent causal story
Dedicated AI workstation engineered for researchers and academic teams. Fully compliant with Nature, Science, Cell, and ACS visual standards. Accurately decodes complex upstream/downstream cascades in 12 seconds.
Empowering the complete research lifecycle from literature extraction to manuscript submission.
Upload PDF papers or abstracts; AI extracts core discoveries and experimental findings into top-tier figures.
Generate publication-grade mechanisms, signaling cascades, and subcellular structures compliant with journal guidelines.
Upload existing literature figures or sketches; AI extracts the layout and redraws in top-tier journal aesthetics.
Designed for grant proposals and thesis defenses, organizing milestones into structured technical roadmaps.
Create CONSORT clinical trials and omics workflows with integrated Draw.io interactive vector editing and SVG export.
Volcano plots, heatmaps, UMAP/t-SNE clustering, and KM curves with refined journal color palettes.
Actual publication-grade illustrations generated by our system. Click to inspect high-resolution details or replicate with one click.
tumor cells, CD8+ T cells, TAM macrophages, the PD-1/PD-L1 immune checkpoint, anti-PD-1 therapy, cytotoxic killing, and tumor apoptosis as one coherent causal story
intravenous LNP delivery, cellular uptake, endosomal acidification, ionizable-lipid protonation, membrane fusion, mRNA release, ribosomal translation, and target protein expression
patient samples, tissue dissociation, scRNA-seq and scATAC-seq, cell clustering, lineage states, regulatory networks, resistant subpopulations, and clinical associations
dietary fiber, gut microbiota, short-chain fatty acids, intestinal barrier, circulation, blood-brain barrier, microglial state, and neuroinflammatory outcomes
target DNA, sgRNA, Cas9 nickase, deaminase, target base conversion, mismatch repair, bystander-edit control, and functional rescue
visible-light excitation, heterojunction band alignment, electron-hole separation, interfacial transfer, HER hydrogen evolution, OER oxygen evolution, and surface active sites
proximal-tubule SGLT2 inhibition, glucosuria and natriuresis, reduced volume load, improved myocardial energetics, lower oxidative stress, and attenuated ventricular remodeling
CAR architecture, tumor-antigen recognition, immune synapse, CD3-zeta and costimulatory signaling, granzyme B/perforin release, Fas-FasL, and tumor-cell apoptosis
fatty-acid overload, mitochondrial stress, ROS, hepatocyte injury, Kupffer-cell activation, inflammatory cytokines, hepatic-stellate-cell activation, collagen deposition, and fibrosis
GLP-1R binding, Gs protein, adenylyl cyclase, cAMP, PKA/Epac2, KATP channels, membrane depolarization, calcium influx, and insulin-vesicle exocytosis
bispecific antibody binding CD3 and a tumor antigen, immune-synapse formation, T-cell activation, cytotoxic-granule release, tumor-cell lysis, and cytokine feedback
System Xc-minus, glutathione synthesis, GPX4, PUFA-phospholipids, ACSL4, labile iron pool, Fenton chemistry, lipid ROS accumulation, and membrane failure
growth factor, RTK, PI3K, PIP3, AKT, TSC1/2, mTORC1, S6K, 4E-BP1, and proliferation/protein-synthesis outputs
hypoxia, PHD/VHL suppression, HIF-1alpha stabilization, nuclear translocation, HRE binding, GLUT1/LDHA/VEGFA transcription, glycolysis, and angiogenesis
DNA damage, ATM/ATR, CHK1/2, p53 stabilization, p21 cell-cycle arrest, BAX/PUMA apoptosis, and recovery after repair
TGF-beta ligand, TGFBR2/TGFBR1 complex, SMAD2/3 phosphorylation, SMAD4 binding, nuclear translocation, and EMT-related gene expression
tumor cells, cancer-associated fibroblasts, IL-6 secretion, IL6R/gp130, JAK-STAT3, ECM remodeling, immunosuppression, invasion, and bidirectional feedback
Wnt receptors, beta-catenin stabilization, YAP/TAZ nuclear translocation, TEAD, shared target genes, stemness, proliferation, and positive/negative crosstalk nodes
apical and basolateral hepatocyte polarity, bile canalicular lumen, tight junctions, bile-salt transporters, sinusoid, and transport directions
outer membrane, inner membrane, cristae, intermembrane space, matrix, complexes I-IV, ATP synthase, proton gradient, and ATP-production direction
tumor core, invasive margin, vessels, hypoxic region, CAFs, T cells, macrophages, ECM, and their spatial relationships
Fab, Fc, heavy chain, light chain, hinge, disulfide bonds, antigen-binding sites, and bispecific engineering junctions
inorganic core, polymer shell, PEG, targeting ligand, loaded drug, pH-responsive linker, size annotation, and release direction
inlet, serpentine mixer, cell-focusing channel, capture chambers, valves, outlet, flow direction, and key dimensional hierarchy
patient tissue collection, digestion, organoid culture, expansion, dose-gradient treatment, viability assay, imaging, sensitivity scoring, and candidate selection
study centers, recruitment, baseline assessment, exposure stratification, follow-up points, primary endpoint, loss-to-follow-up handling, statistical analysis, and sensitivity analysis
sgRNA design, vector construction, transfection, selection, single-clone isolation, genotyping, Western blot, and functional validation
cell preparation, orthotopic implantation, randomization, dosing time points, tumor monitoring, endpoint definition, tissue collection, immunohistochemistry, and survival analysis
blood collection, cell-removal centrifugation, SEC or ultracentrifugation, exosome validation, lysis, protein quantification, digestion, desalting, LC-MS/MS, and database search
Day 0 implantation, tumor-threshold trigger, randomization, fractionated radiotherapy, anti-PD-1 dosing, serial blood collection, imaging, endpoint sampling, and long-term survival follow-up
eligibility assessment, exclusion reasons, randomization, intervention and control arms, loss to follow-up, discontinuation, analyzed populations, and clear N placeholders
diagnosed patients, tissue/liquid biopsy, NGS testing, actionable-variant decision, molecular tumor board, matched trial, unmatched cohort, and follow-up
screening, washout, 1:1 randomization, treatment arm, placebo arm, blinding, primary endpoint, secondary endpoints, safety follow-up, and analysis sets
nodule size and morphology, patient risk factors, low-dose CT follow-up, PET-CT, biopsy/bronchoscopy, surgical evaluation, and benign/malignant outcomes
early versus metastatic stratification, neoadjuvant therapy, surgery, pCR decision, adjuvant regimen, sequential anti-HER2 therapy after recurrence, and brain-metastasis branch
HFrEF/HFmrEF/HFpEF, NT-proBNP level, renal function, atrial fibrillation, diabetes, congestion status, risk level, and treatment priority
FASTQ QC, adapter trimming, alignment, count matrix, normalization, differential analysis, volcano/heatmap outputs, GO/KEGG/GSEA, and candidate validation
tissue dissociation, single-cell capture, library sequencing, QC, doublet removal, normalization, dimensionality reduction, clustering, marker calling, cell annotation, and differential-state analysis
tissue sectioning, H&E imaging, spatial capture, sequencing, spot QC, spatial clustering, region annotation, cell-type deconvolution, and spatial ligand-receptor analysis
three omics inputs, per-omics QC and differential analysis, ID mapping, batch correction, correlation networks, pathway-level integration, latent-factor modeling, and biomarker candidates
EHR, imaging and omics inputs, missing-data handling, feature engineering, train-validation-test split, cross-validation, model comparison, SHAP explanation, external validation, and deployment
WSI slides, tissue detection, patching, stain normalization, feature encoding, MIL aggregation, classification/prognosis task, internal validation, external cohort, and interpretability heatmaps
x-axis log2 fold change, y-axis -log10 adjusted P, distinct significant up/down colors, threshold guide lines, labels for top genes, and a concise legend
genes as rows, samples as columns, z-score scale, hierarchical dendrograms, sample-group annotation bars, highlighted gene modules, and concise legends
2D UMAP embedding, major cell types in distinct colors, clear cluster boundaries, representative marker labels, and a small companion panel for patient/condition source
time axis, PFS probability, two step curves, censor marks, number-at-risk table, HR with 95% CI, and appropriately placed log-rank P value
subgroup labels, sample sizes, HR/OR point estimates with 95% CI, null line, overall-effect diamond, interaction P values, and left/right benefit direction
first-line, second-line and third-line treatments, response/progression/discontinuation outcomes, link widths proportional to patient counts, nodes grouped by treatment class, and N labels
Actual publication-grade illustrations generated by our system. Click to inspect high-resolution details or replicate with one click. The taxonomy keeps Chinese and English scientific terms together for researchers, search engines and generative discovery systems.
Integrated Nature biomedical palettes, Science high-contrast cool tones, Cell red-blue palettes, and BioRender guidelines, eliminating amateurish neon colors.
Intelligently extracts molecular targets, subcellular compartments, receptor-ligand interactions, and pathway cascades with impeccable academic logic.
Upload literature screenshots or iPad hand-drawn sketches; AI extracts composition skeletons and redraws them in publication-grade quality.
Supports standard academic aspect ratios (1024x1024, 1536x1024, 2560x1440) with noise-free high resolution, fully meeting print submission specs.
Experience AI-empowered scientific visualization and generate publication-grade mechanism figures in minutes.
Start Scientific Drawing FreeUse it to draft mechanism diagrams, graphical abstracts, signaling pathways, experimental workflows and research roadmaps, then review and edit labels, nodes and scientific relationships.
The workflow provides editable figures and export options. Before submission, verify scientific accuracy, labels, resolution and the target journal's figure requirements.